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2:51
CBS News
Clinical trials underway for potential drug to stop cytokine storm in COVID-19 patients
Doctors have many unanswered questions about how the coronavirus attacks the body. One potential treatment focuses on drugs that help regulate a patient's immune response to the virus, stopping it from causing the inflammation that can result in devastating consequences. CBS News senior medical correspondent Dr. Tara Narula looks at one ...
May 19, 2020
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Sepsis/shock unleash DAMPs/PAMPs, triggering a cytokine storm (SIRS) that causes endothelial damage, microvascular thrombosis, and hypoperfusion. This culminates in multi-organ dysfunction: neurologic (encephalopathy), respiratory (ARDS), cardiovascular (vasoplegia, myocardial depression), AKI, hepatic dysfunction, GI ileus/translocation, and coagulopathy. Early, aggressive intervention is critical. Ref: Mosier et al. J Trauma Acute Care Surg. 2024;97(6). #Sepsis #MOF #CriticalCare #MedEd | Abda
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