Porphobilinogen (PBG) is an organic compound that occurs in living organisms as an intermediate in the biosynthesis of porphyrins, which include critical substances like hemoglobin and …

Feb 3, 2025 · Porphobilinogen (PBG) is one of several types of porphyrins found in your body. Porphyrins help form many important substances in the body. One of these is hemoglobin, the …

Aug 5, 2024 · Acute intermittent porphyria (AIP; also called Swedish porphyria, pyrroloporphyria, intermittent acute porphyria) is an acute hepatic porphyria resulting from a partial deficiency of …

The porphyrin precursors porphobilinogen (PBG) and aminolevulinic acid (ALA) and porphyrins are readily measured in urine. Normal urine contains appreciable amounts of these …

Urinary porphobilinogen (PBG) is elevated during the acute phase of the neurologic porphyrias. Urine and fecal porphyrin analysis should be performed to confirm the diagnosis and to …

Porphobilinogen synthase (PBGS, EC 4.2.1.24) catalyzes the first common reaction in the biosynthesis of all the tetrapyrrole pigments (e.g., heme, chlorophyll, B12, etc.) and thus is an …

Jun 13, 2005 · Porphobilinogen is a pyrrole involved in porphyrin metabolism. It is generated by the enzyme ALA dehydratase, and converted into hydroxymethyl bilane by the enzyme …

First-order test for evaluating a suspected acute porphyria: acute intermittent porphyria, hereditary coproporphyria, and variegate porphyria. For more information see: - The Heme Biosynthetic …

Porphobilinogen is a pyrrole involved in porphyrin metabolism. It is generated by the enzyme ALA dehydratase, and converted into hydroxymethyl bilane by the enzyme porphobilinogen …

Porphobilinogen (PBG) is one of several types of porphyrins found in your body. Porphyrins help form many important substances in the body. One of these is hemoglobin, the protein in red …