Objective While guidelines advocate renin-angiotensin system inhibitors (RASi) for renoprotection in lupus nephritis (LN), ...

Objective Hydroxychloroquine (HCQ) is a cornerstone therapy for SLE, reducing flares, organ damage and mortality. However, ...

Objective SLE is a heterogeneous systemic autoimmune disease with diverse clinical manifestations. We aimed to identify ...

Objective To examine the impact of different disease activity states (DAS) on outcomes in a longitudinal inception childhood-onset SLE cohort. Materials and methods Three DAS were included—remission: ...

Objective This study aimed to characterise the clinical features and treatment regimens of patients with lupus who have lymphadenopathy (LAP), as well as to investigate the presence and potential ...

Introduction Childhood-onset systemic lupus erythematosus (cSLE) is associated with significant morbidity and mortality. While numerous variants have been associated with adult-onset SLE, limited data ...

Background/Purpose Juvenile lupus (JSLE) and dermatomyositis (JDM) are independent predictors of cardiovascular disease (CVD). The American Heart Association (AHA) defines cardiovascular health (CVH) ...

Objective To determine the feasibility and risk of flares by achieving successful glucocorticoid (GC) tapering during the first year of juvenile SLE and the value of early achievement of childhood ...

Objective To determine whether clinically inactive/low-activity SLE reflects immunological remission in this cross-sectional study using CD180 (RP105)-anchored, stage-resolved profiling of peripheral ...

Objectives To assess the effectiveness and safety of baricitinib in the treatment of Rhupus. Methods We conducted a retrospective observational review of medical records from the Rheumatology ...

We present the case of a 34-year-old with SLE treated initially with hydroxychloroquine (200 mg/daily) and low dose of glucocorticoids(GC). The autoimmune profile revealed positivity for ...

Objective Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterised by heterogeneous clinical manifestations, autoantibody production and epigenetic dysregulation in T cells. We ...