A woman in her 70s on pembrolizumab for non-small cell lung cancer experienced progressive fatigue, intractable nausea and reduced mobility since commencing her cancer treatment. After repeat ...

We describe the case of a middle-aged man with stage IV metastatic melanoma receiving ipilimumab/nivolumab combination therapy. Two weeks after receiving his third cycle of treatment, he presented to ...

Tizanidine, a muscle relaxant, exerts its mechanism as a centrally acting alpha-2 adrenergic receptor agonist and binds to imidazoline receptors. Bradycardia and hypotension are adverse effects ...

Obstructive hydrocephalus is a rare complication of pituitary prolactinomas, especially in women, where symptoms of amenorrhoea rarely go unnoticed. In this study, a case of a female in her 20s with a ...

Air embolism is a rare complication of endovascular procedures with hyperbaric oxygen therapy (HBOT) as a potential treatment. We report a male patient in his 40s presented to the emergency department ...

Exogenous progesterone aids in enhancing embryo implantation and consequently pregnancy rates, which makes it crucial for both establishing and sustaining pregnancy during in vitro fertilisation (IVF) ...

Acute idiopathic scrotal wall oedema is an uncommon cause of acute scrotal oedema that usually affects the paediatric population and is rarely encountered in adults. It frequently goes away without ...

Metformin-associated lactic acidosis (MALA) is a rare and potentially life-threatening complication of metformin use. It typically occurs in patients who are diabetic and also have other risk factors ...

We present a case of a male in his early 50s assessed in the emergency department with a seemingly clear alcohol history but with classic symptoms of Wernicke’s encephalopathy (WE): disorientation, ...

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome and haemophagocytic lymphohistiocytosis (HLH) are rare but severe immune-mediated diseases with overlapping clinical ...

A woman in her late 30s presented with a large left-sided labial swelling at a tertiary maternity and gynaecology hospital. The swelling had been present for more than 10 years, and had previously ...

Valproate (VPA) is broad-spectrum antiepileptic drug. Several adverse reactions including hepatotoxicity, fetal risk and pancreatitis are well known and labelled as boxed warnings in the USA. One ...