One of the most intriguing and consequential games of the college football weekend kicks off Saturday afternoon in Eugene, OR where the 6th-ranked Ducks host the No. 16 Trojans of USC (8-2). There are significant College Football Playoff implications for both teams.

With the Oregon Ducks entering their second to last game of the 2025 regular season against the USC Trojans, several college football analysts are calling this match-up a decider for the College Football Playoffs.

Throughout the 2025 campaign, the Oregon Ducks have continued making their rounds of meeting Big Ten opponents for the first time as a member of the conference, often with select matchups prior to then. But in Week 13 against the USC Trojans, that won't be the case.

Find single game tickets to the Oregon Ducks vs. USC Trojans college football Week 13 matchup on Saturday, November 22, 2025 at Autzen Stadium.

The Oregon Ducks have one of the best defenses in the country, and the numbers prove it. They are currently the No. 6 scoring defense and the No. 3 defense in