A team of engineers at the University of Florida has developed a new form of CRISPR technology that could make diagnostics ...

A team of researchers has uncovered a key cellular mechanism that affects the function of mRNA vaccines and therapeutics. Their study provides the first comprehensive understanding of how mRNA ...

Madrigal licensed ARO-PNPLA3 from Arrowhead for $25 million upfront and up to $975 million in milestones, expanding a liver-directed siRNA portfolio intended to pair with resmetirom. PNPLA3 silencing ...

Bacteria fend off invading viruses with molecular scissors that slice up viral DNA—a system called CRISPR that's become ...

Advanced non-viral gene delivery systems are expanding the range of indications and therapy modalities possible for the new generation of genetic medicines.

Moderna is launching a large-scale clinical trial of a shot to combat bird flu in humans after Health and Human Services Secretary Robert F. Kennedy Jr.’s department had canceled hundreds of millions ...

The advent of mRNA vaccines against SARS-CoV-2 in 2020 changed the course of the COVID-19 pandemic. Now, the Nobel Prize–winning technology is being adapted to fight cancer, with mRNA vaccines in ...

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RNA therapeutics are expanding rapidly, driving demand for manufacturing processes that can keep pace with clinical translation. Because mRNA yield and impurity profiles are jointly influenced by ...