Plastic and thus modifiable neurons lose their function at old age, new research in fruit flies reveals.

While probing the escape reflex in the fruit fly Drosophila, researchers at Johannes Gutenberg-University Mainz (JGU) and the ...

Scientists have developed a computer-based model that may explain how nerve cells become damaged in ALS, and how best to time ...

M. Carmen Varela, BSc, BA, explains how a novel human organoid model enables large-scale production of PV interneurons.

For decades, dopamine has been celebrated in neuroscience as the quintessential "reward molecule"—a chemical herald of pleasure, motivation, and reinforcement. In popular understanding, higher ...

Researchers identify two key proteins that allow chandelier cells to connect with excitatory neurons. This "handshake" regulates brain signals and, when disrupted, may lead to epilepsy or autism.

Scientists discovered that high-fat junk food disrupts memory circuits in the brain almost immediately. Within just four days, neurons in the hippocampus became overactive, impairing memory. Restoring ...

Miniature models of the brain have revealed a "previously unappreciated" role of microglia, a type of cell found within the organ. The finding could help unpack how disorders such as autism arise.

The anterior cingulate cortex (ACC) is essential for social behavior, and its dysfunction is implicated in social interaction deficits in autism. Pyramidal neuron activity in the ACC is modulated by ...

Background: Neuronal circuitry remodeling which compromises excitatory and inhibitory neurons is critical to improve neurological outcome after stroke. Cerebral endothelial cell (CEC) generated small ...