Cancer's secret safety net: A hidden mechanism lets dangerous mutations thrive

Researchers in Class of 1942 Professor of Chemistry Matthew D. Shoulders' lab have uncovered a sinister hidden mechanism that ...

Exploring mutations that spontaneously switch on a key brain cell receptor

Many people are familiar with histamine, a biological molecule that serves as a key driver of allergic reactions and other ...
Science Daily

Mutations in noncoding DNA become functional in some cancer-driving genes

Despite progress in defining functional elements of noncoding DNA, it is still not fully understood. Researchers, using an experiment that elucidated the function of tens of thousands of noncoding ...
Los Angeles Times

Genetic medicine can leave people with rare mutations behind. But there’s new hope

Emily Kramer-Golinkoff can’t get enough oxygen with each breath. Advanced cystic fibrosis makes even simple things like walking or showering arduous and exhausting. She has the most common fatal ...
Science Daily

Cancer-like mutations in healthy cells point to origins of breast cancer

Researchers have pinpointed what could be the early genetic origins of breast cancer -- cancer-like mutations appearing in the cells of healthy women. In a new study, the international collaborators ...
Fred Hutch

Surprising findings about blood cell mutations bode well for transplant recipients

After an allogeneic stem cell transplant, a recipient’s body faces a daunting task: rebuilding the person’s blood-forming and immune systems from the ground up from a relatively small number of “seed” ...
Newsweek

Men’s Harmful Sperm Mutations Increase With Age—Study Reveals Hidden Cause

While men may be able to have children much later than women, doing so could come with an increased risk of inherited disease for their children. Researchers from the Wellcome Sanger Institute have ...