Most constipation is harmless. In rare cases, the colon can become dangerously enlarged. Here is what you need to know.

An 8-month-old infant with severe genetic epilepsy has become the first patient in the world to receive an experimental gene replacement therapy designed to restore the function of the WWOX gene ...

Healthbeat reports that a recent ByHeart baby formula botulism outbreak left many hospitalized infants needing ongoing ...

Ironwood Pharmaceuticals IRWD announced that the FDA has approved the expanded use of its sole marketed drug, Linzess ...

The FDA expanded its approval of linaclotide to include pediatric patients aged 2 to 5 years with functional ...

Phase 3 data support a lower age threshold for linaclotide, making it the first prescription therapy approved for functional constipation in patients ages 2 to 5.

Duke and UNC researchers are teaming up on a $12.9 million national clinical trial that zeroes in on a problem many families of autistic children quietly battle every day: chronic constipation. The ...

The agreement ends a three-year battle over transgender healthcare at the country’s largest children’s hospital. Advocates for trans rights raised concerns about politics shaping medicine.

Three clinically available drugs could pave the way for safer and more effective treatments for one of the most aggressive forms of childhood leukaemia, a new study suggests. In research conducted in ...

Everybody poops, but some of us have a harder time of it than others. Constipation—infrequent (less than three times a week) or difficult passage of stool—affects an estimated 26 percent of women and ...

BACKGROUND: Functional constipation is characterized by a set of symptoms including hardened stools, abdominal discomfort, a tendency to retain stools, and eventual fecal incontinence. This condition ...

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