The San Francisco 49ers defense struggled some against the Tennessee Titans, but their offense had a huge day to mark the ...

The 49ers scored on their first five possessions and seven of eight in the game, with only a fumble marring their streak.

The Titans found more success on their second drive, picking up 17 yards and a couple of first downs. They were in San ...

Brock Purdy threw a one-yard TD to George Kittle that extended the San Francisco 49ers lead to 31-10 over the Tennessee ...

Tennessee Titans' Jeffery Simmons caught his second career TD that trimmed the deficit against the San Francisco 49ers to 31-17.

Although Brock Prudy and the San Francisco 49ers have dealt with many health issues throughout the season, they still find ...

The Indianapolis Colts visit the Seattle Seahawks in NFL Week 15 action: Live updates, score, highlights, Philip Rivers stats ...

San Francisco 49ers quarterback Brock Purdy goes airborne on a jump pass for his third touchdown toss of the game, a 1-yard ...

Los Angeles Rams outside linebacker Josaiah Stewart tackles Detroit Lions running back Jameson Williams after a 1-yard rush ...

NFL week 15 live updates, scores, results and live radio commentary as the Kansas City Chiefs miss the play-offs, Philip ...

Losing a game against a team with a 2-11 record can be a recipe for disaster for a team in the middle of a playoff hunt.

Purdy was pushing the ball to all corners of the field, picking up first downs — and more — with his scrambling ability, and keeping the Niners in the right looks against a Tennessee defense that has ...