Amy Lesakowski is now a 15 year cancer survivor. She and her husband now run the 11 Day Power Play, an annual marathon hockey event raising money for cancer research.

High pressure will settle over the area for the next several days. You can expect a great stretch of fall weather for the area through the weekend.

Students at the University at Buffalo Jacobs School of Medicine have partnered with organizations to push to register AEDs ...

Sidney Crosby scored a power-play goal at 1:38 of overtime and the Pittsburgh Penguins rallied to beat the Buffalo Sabres 6-5 ...

Allison Kwilos and Katie Marsh bond for life after a chance meeting at a local tavern led to a life-saving kidney donation ...

Imagine going 10 MPH over the speed limit and your car alerts you to slow down. That's what New York State Assemblyman Robert Carroll hopes is the future for New York vehicles.

Is there a remedy for the struggling pharmacy industry? Employees and customers hope the answer is yes and it kicks in quickly before more pharmacies are forced to close their doors.

The Buffalo Sewer Authority joined community stakeholders Wednesday to announce the "Queen City Clean Waters" initiative.

After nearly 20 years in office, former Buffalo mayor Byron Drown stepped down from office Tuesday morning and started his ...

The American Revolution is taking center stage in Downtown Buffalo with Hamilton taking over Shea's Performing Arts Center.

In six games, the wide receivers on the Bills roster have combined for just 53 catches. The motto "everybody eats" made sense in theory, but the results painted a different picture.

Olean Police are asking for the public's help finding this pickup truck. Police said the silver-colored truck is part of an investigation into the shooting of an 11-year-old child on Tuesday.