One year ago, the PHG Foundation report, Host genomics: lessons for infectious diseases, highlighted the promise of host genomics research for infectious disease. Policy priorities may have changed ...

Following the successful completion of the NHS national pilot in April 2025, the highly anticipated first results assessing CYP2C19 genetic testing to guide clopidogrel use in ischaemic stroke and TIA ...

The optimism is not unfounded. In specific, well-defined clinical scenarios, polygenic scores are beginning to demonstrate some tangible utility. For cardiovascular disease, MI-GENES, a 10-year follow ...

Catherine Barnard, FBA, FLSW, FRSA is Professor of European law and fellow of Trinity College, Cambridge and Director of the Centre for European Legal Studies. She is the author of EU Employment Law ...

Babb de Villiers C, Plans-Beriso E, Erady C, Blackburn L, Wilson H, Turner H, Kuhn I, Barahona-López C, Diez-Echave P, Hernández OR, et al. Biomarkers for Personalised Primary or Secondary Prevention ...

A patient arriving in A&E or another clinical setting, with suspected or known infection and the risk of sepsis, requires immediate action. Antibiotic admission more than one hour after suspected ...

The sepsis definition describes three elements: infection, the host response and life-threatening organ dysfunction. Diagnosis is made based on myriad signs and symptoms, and although infection ...

Sepsis is a critical global healthcare challenge, marked by complex and rapidly evolving symptoms, which can escalate with alarming speed leading to multi-organ failure. This leaves only a narrow ...

Prof Ahmed is a distinguished public health physician, epidemiologist, and global health diplomat with over three decades of experience spanning clinical medicine, academia, and public health policy ...

The term ‘mainstreaming’ was first used in 2003 by the Secretary of State for Health in the context of the genetics white paper Our Inheritance, Our Future when he argued that genomics must move from ...

Cost-utility studies provide critical information for the costs and benefits of using any new test, typically building on existing public health and screening programmes, within a defined population.

The Wellcome Trust recently announced that they are funding a research programme to investigate synthetic human genomes, and Laura Blackburn, PHG Foundation’s Head of Science, had the opportunity to ...