Alzheimerologists, it is time to update your GWAS catalogue—again. In June 3 Nature Genetics, a staggering 508 scientists (yes, we counted) from across the United States and Europe, led by Céline ...
Professional Information Research FellowMonash University Brain Waste, Please Proceed to Your Nearest Exit 29 May 2026 ...
When the RNA-binding protein TDP-43 absconds from the nucleus, splicing chaos ensues and neuronal function gets disrupted in ways scientists are still cataloguing. Now on this list: synaptic ...
Jae-Sung Lim, Ph.D. University of Ulsan College of Medicine Contact Information Jae-Sung Lim, Ph.D. Seoul, Korea, Republic of ...
Low dose interleukin 2 is being tested as an immunomodulatory approach in neurodegenerative diseases. It increases the number and activity of regulatory T cells (Tregs) that suppress inflammation. At ...
Professional Information Graduate Student in Mathematics and NeurosurgeonMississippi State University Education BS biochemistry Tulane MD Tulane ...
Can brain amyloid reduction be used as a surrogate biomarker of clinical benefit? This is a hotly debated question in the field (see Dec 2024 discussion). A recent post hoc analysis of Phase 3 ...
Sit down, brain—a different organ takes the mic in a new study on the Christchurch variant of ApoE3. In the May 6 Neuron, scientists report that the liver cleared more brain amyloid when it produced ...
The world did not end today as predicted, but unfortunately we have to report that development of another potential drug did. Allon Therapeutics Inc. announced 19 December that its drug candidate ...
S-acylation, the posttranslational addition of fatty acids, such as palmitate, to proteins, seems to be having a moment. Earlier this month, Sreeganga Chandra of Yale University in New Haven, ...
The family tree of tau filament folds continues to sprout new branches. With them come new questions. At the Tau Global Conference, held May 14-15 in Washington, D.C., scientists grappled with the ...
After a stroke, microglia transform into a reparative workforce. They release growth factors, coax synapses to regrow, and nudge damaged axons to remyelinate. Alas, this spontaneous recovery process ...
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