Background Endoscopic submucosal dissection (ESD) enables en bloc resection of early gastrointestinal cancers and provides ...

Tissue epithelia maintain their lineage identity under normal conditions but occasionally undergo ‘reprogramming’ into ...

We read the global analysis of chronic kidney disease (CKD) in cirrhosis by Wong et al with great interest.1 Assembling 7040 ...

Correspondence to Dr Gyongyi Szabo, Department of Medicine, Division of Gastroenterology, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA; gszabo1{at}bidmc.harvard.edu Objective Alcohol ...

I read the GOULASH trial with great interest. This multicentre, double-blind randomised clinical trial compared early high-energy enteral nutrition (30 kcal/kg/day) with a gradually increasing energy ...

Background: The available classifications of gastritis are inconsistently used, possibly because none provides immediate prognostic/therapeutic information to clinicians. As histology reporting of ...

Background Hepatocellular carcinoma (HCC), one of the most prevalent cancers worldwide, has a high mortality owing to diagnostic challenges and therapeutic resistance. Lactate metabolism and protein ...

4 Department of Hepatogastroenterology, Hopital Claude Huriez, CHRU Lille, France Correspondence to: Professor J-F Colombel Department of Hepato-Gastroenterology, Hopital Claude Huriez, CHRU de Lille, ...

Background The optimal timing of endoscopic retrograde cholangiopancreatography (ERCP) in patients with mild-to-moderate acute cholangitis remains uncertain. Objective To compare the clinical outcomes ...

Background Proteases and histamine, co-secreted by mast cells and bacteria, sensitise colonic nociceptors and contribute to irritable bowel syndrome (IBS) pain. Objective To determine whether ...

Background Lynch syndrome (LS) is the most common hereditary cause of colorectal cancer (CRC) and results from pathogenic germline variants affecting mismatch repair. The tissue microenvironment that ...