Just days before their season opener against the Rams, the 49ers have been dealt a massive blow on the defensive line.

Week 1 kicks off in unusual fashion for these NFC West rivals, with the 49ers and Rams squaring off on Thursday night from ...

However, the 49ers' "biggest concern" for 2026, according to ESPN's Nick Wagoner, is the pass rush production. Even with the return of Nick Bosa, Wagoner still isn't sold on the 49ers being a good ...

Piñeiro became a fan favorite as soon as he joined the 49ers last season, bringing stability, confidence and even some flair ...

San Francisco is going to spend a week in Melbourne, Australia for the opener.

The NFL's first-ever regular season match in Australia at the MCG will feature a half-time show - just like the Super Bowl ...

The 49ers opened preparations for their season opener with an uneven injury picture Monday in Melbourne. Mike Evans was back ...

Kyle Shanahan has warmed to Australia. His grievance with Los Angeles, however, remains fully intact. After spending several ...

The 49ers have held their first practice in Australia in advance of their Week 1 showdown against the Rams on Thursday.

San Francisco 49ers player Brayden Willis endured a gruelling 16-hour flight to Melbourne , only to be cut from the team ...

San Francisco 49ers wide receiver Mike Evans downplays his training camp injuries and says that if it was a game week, he ...

The 49ers received troubling news as superstar Christian McCaffrey missed a crucial portion of practice just days before the ...