San Francisco 49ers head coach Kyle Shanahan said he had big comebacks in mind when he kept Christian McCaffrey on the field ...

San Francisco 49ers running back Christian McCaffrey set a new NFL record in the team's Week 11 win over the Arizona ...

» Not only did the Niners’ tight end catch a touchdown of his own, but he was instrumental on the 49ers’ third touchdown of ...

There are always a few things to learn from the San Francisco 49ers in every win or defeat. That includes an expected 41-22 ...

SANTA CLARA, Calif. (AP) — Brock Purdy returned to the lineup and the San Francisco 49ers scored their most points in nearly ...

The San Francisco 49ers notched a fairly impressive, and expected, win against the Arizona Cardinals. It was a nice rebound ...

The 49ers' team captains stepped up in Arizona. One of them, George Kittle, said the team is positioned right where it needs ...

San Francisco 49ers WR Skyy Moore reflected on his 98-yard opening kickoff return and shared his reaction to the Faithful ...

Brock Purdy returned from a six-game absence to throw three touchdowns as the 49ers (7-4) romped to a 41-22 win over the host ...

So much went right — and some went wrong — as the 49ers walloped the host Arizona Cardinals 41-22 in Brock Purdy’s comeback.

Arizona had the passing game working, but it didn't matter in a 41-22 loss to San Francisco at State Farm Stadium in Glendale ...

We’re almost through bye weeks, and the league playoff picture is starting to take shape. We only have one new addition to ...