The Bills are back on Thanksgiving for the first time since 2022

The NFL has released the 2026 schedule, and the Buffalo Bills have seven prime-time games this year, including games on Thanksgiving and Christmas.

The Buffalo Bills won't have to wait long to test the lights at new Highmark Stadium. Buffalo's newly released 2026 schedule opens with a road trip to Houston before the Bills return home for a Week 2 Thursday Night Football game against the Detroit Lions in the first regular-season game at the new stadium.

The AFC’s best matchup during the past six seasons has been the Kansas City Chiefs against the Buffalo Bills. Quarterbacks Patrick Mahomes and Josh Allen provide plenty of star power. The two teams have met in the playoffs four

To no surprise, the Buffalo Bills earned the maximum number of six primetime exposures on their 2026 schedule. In somewhat of a surprise, Buffalo was given a seventh standalone game on Christmas Day.

Detroit Lions 2026 schedule in Week 2 will see them visit Buffalo Bills on Thursday Night Football in opener of the new $2.2 billion Highmark Stadium.

The NFL has announced key matchups for the 2026 season, including the Buffalo Bills' debut at their new stadium and notable games for the Dallas Cowboys.

Earlier this week, the 2026 NFL schedule was announced and while the Buffalo Bills and the rest of the league already knew who their opponents would be, they now know when they will face each one.