Hiroshima University researchers have demonstrated a proof of concept for the mass production of genome-edited T cells that ...

For the immune system to effectively combat pathogens, antibody responses must be precisely controlled. So-called follicular ...

For the immune system to effectively combat pathogens, antibody responses must be precisely controlled. So-called follicular ...

For the immune system to effectively combat pathogens, antibody responses must be precisely controlled. So-called follicular regulatory T cells (Tfr cells) play a key role in this process by limiting ...

For the immune system to effectively combat pathogens, antibody responses must be precisely controlled. So-called follicular ...

A woman who had three different autoimmune conditions has not required treatments for almost a year after her immune cells were genetically modified and used to kill off the rogue cells attacking her ...

In desperation, the woman’s care team reached out to Müller, a hematologist-oncologist at the University Hospital of Erlangen, a roughly three-hour drive away by ambulance. In recent years, he and his ...

A CAR-T cell therapy has successfully treated not one, not two, but three different autoimmune diseases at once in a patient, providing further proof of the modality’s promise in the disease area as a ...

Creating artificial systems that mimic the functioning of cells is one of the goals of what is known as synthetic biology. These models, known as synthetic or biomimetic cells, allow some of the basic ...

In a new study published in Science titled, “Mitochondrial metabolism and signaling direct dendritic cell function in antitumor immunity,” researchers from St. Jude Children’s Research Hospital have ...

For years, one of the most powerful weapons against certain blood cancers, called CAR-T therapy, has required an elaborate process: Doctors extract a patient’s immune cells, ship them to a specialized ...

The study, “Integration of phospho-signaling and transcriptomics in single cells reveals distinct Th17 cell fates,” was published in Cell Reports. In the study, first author Seth Fortmann, M.D., Ph.D.