No gene acts alone: interacting variants and protein partnerships can worsen, mask or even rescue disease risk, demanding ...

In natural populations, the mechanisms of evolution do not act in isolation. This is crucially important to conservation geneticists, who grapple with the implications of these evolutionary processes ...

ISLAND LIFE is famously idyllic, but it’s long been known that islanders tend to experience disproportionately high rates of some rare genetically transmitted diseases. Faroe islanders, for example, ...

I have spent years covering discoveries that nudge our origin story around the edges, but the sequencing of DNA from one of the very last Neanderthals does something different: it rewrites the center ...

The Y chromosome is unlike other chromosomes in the human genome. It does not regularly recombine with a matching partner, making it genetically isolated. Over evolutionary time, this isolation has ...

Geographical barriers and cultural differences can prevent people from mingling with their neighbors, leading to genetic isolation — and the phenomenon is more common than most people think. When you ...

Variants of APOE gene, that control brain waste clearance are linked to 90% of Alzheimer’s cases. Targeting its protein can critically prevent dementia risk.

* Evolutionary gene loss has steadily reduced the Y chromosome to a small set of essential genes * Gene// conversion may increase variation but does not restore lost genetic function * Future sex ...