Researchers have unveiled a way to flip genes back on without slicing into the genome, a shift that could make CRISPR far ...

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

The expression of genes has to be carefully regulated in cells; active genes give cells their identity and ability to function. Epigenetic features are just one way that cells control gene expression, ...

To help achieve more precise control of gene therapy, engineers have designed a new control circuit that can keep gene expression levels within a target range. The method could be used to deliver ...

urning genes on and off is like flipping a light switch, controlling whether genes in a cell are active. When a gene is turned on, the production of proteins or other substances is promoted; when it's ...

Scientists from Oxford's Radcliffe Department of Medicine have achieved the most detailed view yet of how DNA folds and functions inside living cells, revealing the physical structures that control ...

Genes make up the blueprints and outline the process of building every living organism. To ensure that the right genes are activated in the right cells, and in the right amounts at the right time, ...

Molecular instructions in living cells can be timed rather like the notes or chords in a piece of music. For example, a finite number of genes can be activated and expressed in different orders, for ...

The study combines a deep learning model with CRISPR screens to control the expression of human genes in different ways -- such as flicking a light switch to shut them off completely or by using a ...

A team led by Tappei Mishina at the RIKEN Center for Biosystems Dynamics Research (BDR) has discovered that parasites manipulate their hosts using stolen genes that they likely acquired through a ...