Certain epigenetic modifications can directly control how genetic material is packed in the nucleus, RIKEN researchers have shown. This has important implications for our understanding of how genes ...
This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...
The serine 31 (Ser31) phosphorylation modification (H3.3S31ph) in the N-terminal tail of the histone variant H3.3 can transform H3.3 nucleosomes from a stable state to a dynamically activated ...
Neurological disorders represent a growing global health challenge, yet the molecular mechanisms underlying their onset and progression remain incompletely ...