Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. CD8 + T cells have critical roles in tumor ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Auxin dictates root architecture via the Auxin ...

Contact of developing sensory organs with the external environment is established via the formation of openings in the skin. During eye development, eyelids first grow, fuse and finally reopen, thus ...

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The spatiotemporal regulation of cAMP can generate microdomains just beneath the plasma membrane where cAMP increases are larger and more dynamic than those seen globally. Real‐time measurements of ...

Taken together, the SPR and crosslinking assays indicate that monomeric Soj directly interacts with DnaA both in solution and bound to DNA, and that the substitutions in the DnaA Sup proteins disrupt ...

This month's cover highlights the article Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation by A.-D. Brunner, M. Mann and colleagues. A new ultra-high ...

Here we describe a new signaling cross‐talk between the Vav/Rac1 and Ras pathways that is established through the stimulation of RasGRP1, an exchange factor for Ras subfamily GTPases. This interaction ...

Precursor protein targeting toward organellar surfaces is assisted by different cytosolic chaperones. We demonstrate that the chloroplast protein translocon subunit Toc64 is the docking site for Hsp90 ...

Cell membranes are fascinating supramolecular aggregates that not only form a barrier between compartments but also harbor many chemical reactions essential to the existence and functioning of a cell.

A jackal hunting mice at Etosha National Park, Namibia. The photographer, Hanna Kraus, is a PhD student at the Department of Molecular Evolution and Development of the University of Vienna. Her ...

Type IIB receptor protein tyrosine phosphatases (RPTPs) are bi‐functional cell surface molecules. Their ectodomains mediate stable, homophilic, cell‐adhesive interactions, whereas the intracellular ...