A trial, targeted at people living with obesity from Britain to Puerto Rico, is the first head-to-head comparison of the weight-loss effects of the two blockbuster slimming jabs

More than 200 doctors and specialists have now written to the health secretary to say how stretched NHS obesity treatment services face unprecedented demand from patients wanting these drugs. They warn the injections are only part of what should be a wider package of non-stigmatising care.

Weight-loss jabs are “not the holy grail”, the NHS medical director has said. Prof Sir Stephen Powis said the drugs would be a “revolutionary” part of the approach that Britain takes to obesity. But he said the country “cannot simply treat our way out of the obesity crisis”,