Ayatollah Ali Khamenei has spent almost four decades as Shi'ite Iran's supreme leader building a regional power to rival the Sunni states across the Gulf and implacably hostile to the U.S. and Israel - while crushing repeated unrest at home.

An Iranian state television reporter stopped a live broadcast when an explosion occurred an hour after Israel issued a warning to evacuate the area of Tehran where the TV studios are located.

After Israel attacked Iran, the population has lamented the lack of adequate safety instructions and evacuation orders, turning to social media for answers.

Several people have been injured in the Israeli port city of Haifa, 90km from Tel Aviv, following the latest Iranian strikes, according to Israel's public broadcaster Kan. It added that there is a fire at the scene. Emergency services say there are responding to "several hit sites" following Iran's latest barrage.

In the central Israeli city of Petah Tikva, many people seem to be lining up to support the military operation against Iran — despite an Iranian missile hitting here days ago.

Video shows what appeared to be the moment an Israeli missile hit the Islamic Republic of Iran News Network's studio in Tehran.

It’s key to Iran’s nuclear program: the Fordow plant - in a mountain lair where hundreds of centrifuges, hidden possibly 90 meters underground, enrich uranium to 60%. CNN’s Nick Paton Walsh explains what we know about the key site in Israel’s crosshairs.

The Kremlin responded Monday to remarks by Israeli Prime Minister Netanyahu on possible Iranian regime change, issuing a condemnation of the "actions" that have led to escalated tensions between the two Middle Eastern nations.

The BBC has verified footage showing the aftermath of an Israeli attack on Sunday in the north Tehran neighbourhood of Tajrish Square. After the strike, more verified video shows water flooding the area, with water pipes and sewage systems burst. Columns of smoke can also be seen in the Iranian capital.

Londoners with friends and family in Iran are only able to watch with concern from thousands of kilometres away as conflict continues to escalate between the country and Israel.