Combining picks and building NFL parlays is a common way to try to make a quick buck, but nailing NFL score predictions can be highly profitable. NFL matchups, potential game flow and NFL betting trends should all be taken into consideration before locking in Week 7 NFL game picks.

Before looking at SportsbookWire staff's Week 7 NFL picks, here are the against-the-spread (ATS) and Over/Under (O/U) leaders, according to Teamrankings.com. The Minnesota Vikings (5-0 straight up), who had a bye last week,

There are 15 games on the NFL slate in Week 7, beginning with the Denver Broncos and New Orleans Saints on Thursday, then continuing Sunday for the third and final London game of the season, which has the Jacksonville Jaguars hosting the New England Patriots at Wembley Stadium.