Researchers from the Ottawa HospitalResearch Institute and the University of Ottawa in Canada, along with researchers from the Centre for Genomic Regulation at the Barcelona Institute for Science and ...

Researchers have unveiled the intricate molecular mechanisms governing TCF/LEF-mediated transcription in the canonical Wnt pathway, identifying these proteins as promising therapeutic targets for ...

The four helices conserved across the Lipocone superfamily constitute a cone-like structure, with the helices tending to coalesce on one end and open out into a pocket on the other, lined by the ...

Human cells decode dynamics Wnt signals using an anti-resonant filter that suppresses intermediate-frequency inputs and is capable of redirecting developmental fate outcomes, including germ-layer ...

To investigate whether activating the Wnt/β-catenin signalling pathway differentially promotes fracture healing in aged and adult individuals. CatnbTM2Kem, Catnblox(ex3) and wild-type adult and aged ...

Scientists hope to ‘tackle the disease at its beginnings’ after a genetic breakthrough.