Trace amounts of double-stranded RNA (dsRNA) byproduct produced during in vitro transcription can interfere with downstream in vivo administration by triggering unwanted immune responses. PrimeCap™ T7 ...
Building on its success against COVID-19, mRNA technology holds promise for novel vaccines and treatments targeting various diseases. However, a critical challenge remains: current in vitro ...
SAN DIEGO--(BUSINESS WIRE)--TriLink BioTechnologies and Alphazyme, both part of Maravai LifeSciences, have collaborated to launch CleanScribe™ RNA Polymerase, a novel enzyme that reduces ...
Editor’s note: The following news release is adapted from one originally published by the Broad Institute of MIT and Harvard, which administers the Merkin Prize. UPTON, N.Y. — F. William Studier, a ...
Coliphage N4 virion RNA polymerase (vRNAP), which is injected into the host upon infection, transcribes the phage early genes from promoters that have a 5-bp stem-3 nt loop hairpin structure. Here, we ...
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