Many proteins have a complex architecture that enables biological functions. Molecules can bind to specific sites on a ...

The envelope protein from SARS-CoV-2 (E) is a single pass transmembrane protein which accumulates in the endoplasmic reticulum golgi intermediate compartment in host cells, where it acts as a ...

In a recent study published in the Journal of Experimental Medicine, researchers identified the cellular tropism and transcriptome consequences of severe acute respiratory syndrome coronavirus 2 (SARS ...

The global pandemic may be over, but SARS-CoV-2 continues to infect people around the world. Indeed, the United States has recorded roughly 750 deaths from COVID-19 over the past month. Now, an siRNA ...

UCSF researchers designed new drug candidates that potently block MPro, a viral enzyme that's crucial for SARS-CoV-2 replication. One of these drug candidates, AVI-4516, is shown (center) bound to the ...

Six years after the COVID-19 pandemic, which had claimed over 7 million lives worldwide by April 2024 (figures are no longer being tracked), we are still debating the origins of this novel virus. The ...

In a recent preprint* study posted to the bioRxiv server, a team of researchers analyzed the virological characteristics and epidemiological impact of the Severe Acute Respiratory Syndrome Coronavirus ...

Many proteins have a complex architecture that enables biological functions. Molecules can bind to specific sites on a protein and alter its function. A team at HZB has now investigated the Nsp1 ...