Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

Machine learning models reveal that histone marks are predictive of gene expression across human cell types and highlight important nuances between natural control and the effects of CRISPR-Cas9-based ...

In biology classrooms, we often learn that genes are transcribed into mRNA, which is then translated into proteins—a tidy, linear process. But gene expression in living cells is far more intricate, ...

A new CRISPR-based approach for tuning gene expression up and down allowed identification of how other genes' expression responds to changes of transcription factors.

Understanding human biology requires more than mapping our genes—we must also understand how gene expression is regulated to guide healthy development, growth, and maintenance of our body systems over ...

Northwestern Medicine scientists have discovered how molecular "traffic controllers" in cells influence aging and cellular senescence—a state where cells stop dividing but remain metabolically active.

The SWI/SNF Ig-Fold for Transcription Factor Interactions or 'SWIFT' domain on mSWI/SNF chromatin remodeling complexes engage ...

Vitamin C is a key nutritional component in fruits, yet its concentration often changes dramatically as fruits develop.

A new study led by researchers at UTHealth Houston investigated both gene expression and regulation at single cell levels to reveal disruptions in gene function in three brain regions of patients with ...