News Medical

Gene expression ratio linked to prognosis in solid tumors

A Ludwig Cancer Research study has identified a pair of genes whose expression by a type of immune cell within tumors is predictive of outcomes for cancer patients and is linked to a vast network of ...
Nature

Inflammatory activation is associated with a reduced glucocorticoid receptor alpha/beta expression ratio in monocytes of inpatients with melancholic major depressive disorder

In this study, we used new technology to investigate whether a coherent pattern of enhanced expression of inflammatory and other immune activation genes in circulating monocytes is found in patients ...
ascopubs.org

Prediction of response in advanced breast cancer (ABC) patients who received trastuzumab-paclitaxel (TP): HER2 FISH ratio, expression of class III beta tubulin (bTubIII), and ...

Efficacy of gemcitabine and cisplatin (GP) as first-line combination therapy in patients with triple-negative metastatic breast cancer: Preliminary results report of a phase II trial. Background: The ...
Healio

Gene expression ratio test predicted postsurgical survival for mesothelioma

A four-gene expression ratio test conducted on tissue samples from patients undergoing surgery to treat mesothelioma predicted which patients had the best prognosis for survival. In previous research, ...
ascopubs.org

Prognostic value of the microtubule stability index (MTSI), defined by the quantitative ratio of MAP-tau to stathmin expression, for outcome in breast cancer.

Association of TS and ERCC1 mRNA expressions with overall survival in patients enrolled in CONFIRM 1 and 2. Background: Microtubule associated proteins (MAPs) endogenously regulate microtubule ...