Analysing the gene activity of every single bacterial cell in a colony? A new technique of single-cell transcriptomics developed in W rzburg can do this much more efficiently than other methods: It ...

Bacteria aren’t just mindless microbes. Research by scientists at the Hebrew University of Jerusalem has revealed that single bacterial cells can carry a “memory” of their past environments—passing it ...

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...

The answer depends on the questions you’re trying to answer, as well as the origin, quantity, and quality of your samples. In this article, we’ll briefly discuss several RNA-seq workflows, how they ...

Microcolonies as a window into memory The Microcolony-seq method works by isolating tiny colonies that sprout from individual bacteria, analyzing their RNA, genomes, and physical traits. This approach ...

Antibiotic-driven modifications to ribosomal RNA (rRNA) have been suspected of giving rise to antibiotic resistance. For example, antibiotics can alter methylation patterns in rRNA, changing rRNA ...

The cartoon illustrates how single-cell transcriptomics works: all mRNA molecules are recorded and characterized from countless bacterial cells, which are shown here in survival size on a conveyor ...