Learning a new task, mastering a musical instrument or being able to adapt to the constantly changing environment are all possible thanks to the brain’s plasticity, or its ability to modify itself by ...

A detail of a figure from the paper shows synapses formed between a neuron (above) and muscle (below) a narrow cleft. The distinct T-bar shape indicates an active zone. In the upper image, the synapse ...

The Noelin family of secreted proteins bind to the external portion of AMPA glutamate receptors and stabilize them on the neuronal cellular membrane, a process necessary for transmission of ...

A research team from the Institute of Modern Physics of the Chinese Academy of Sciences and Lanzhou University has obtained ...

Breakthroughs, discoveries, and DIY tips sent every weekday. Terms of Service and Privacy Policy. One of the brain’s most important properties is its flexibility ...

Co-written with Jai Liester. Silent synapses represent one of neuroscience's most fascinating discoveries—connections between neurons that lie dormant until activated by specific triggers. These ...

Clinical portfolio, informed by deep and novel synapse biology and pharmacology insights, aims to strengthen neural connections through event-driven pharmacology Lead candidate zelquistinel is ...

This comprehensive review synthesizes a decade of human and animal research to explain how the gut and brain communicate ...

This is achieved through recruitment and stabilization of additional glutamate receptors at the synapse over time, leading to a sustained signal through the neuron. In the brains of mice lacking ...