The randomized, open-label INSHORE trial (ClinicalTrials.gov Identifier: NCT05627557) evaluated the safety and efficacy of obinutuzumab in children and young adults in clinical remission aged 2 to 25 ...

A post hoc analysis of the STARMEN trial found that a combination of three early biomarkers can predict 2-year remission in ...

Nephrotic syndrome is a group of symptoms that indicate that the kidneys are not functioning as they should. Nephrotic syndrome can result from diseases that affect just the kidneys or the entire body ...

Idiopathic nephrotic syndrome is the most common disorder of glomerular function in pediatrics. [1] Approximately 40% of children diagnosed with idiopathic nephrotic syndrome will have a relapsing ...

For very young children with nephrotic syndrome, longer initial treatment with prednisone didn't offer much benefit, a researcher reported. In a randomized controlled trial of 172 patients ages 1 to 4 ...

Patients with nephrotic syndrome were far more likely than healthy controls to suffer end-stage kidney disease, particularly if they had focal segmental glomerulosclerosis or membranous nephropathy.

With funding from charity Kidney Research UK, Dr Carl May from Bristol Medical School and his team have identified a new treatment pathway for patients with non-genetic (idiopathic) nephrotic syndrome ...

Nephrotic syndrome is a clinical entity defined by heavy proteinuria, hypoalbuminemia, hyperlipidemia, and edema, stemming from various glomerular diseases. Diagnosis requires a comprehensive ...

Please provide your email address to receive an email when new articles are posted on . Compared with a cohort free of kidney disease, patients with primary nephrotic syndrome were nearly 20-times ...

A group led by the Department of Cell Biology at the Kidney Research Center, Niigata University revealed that elevated activity of cdc42 is a critical initiation event leading to proteinuria, and ...