The state of penile tumescence and detumescence is a highly regulated process involving the relaxation and contraction, respectively, of the smooth muscle (SM) within the two corpora cavernosa (CC) of ...

Smooth muscle cells use an actin-myosin II-based contractile apparatus to produce force for a variety of physiological functions, including blood pressure regulation and gut peristalsis. The ...

This is a preview. Log in through your library . Abstract Although it is generally believed that phosphorylation of the regulatory light chain of myosin is required before smooth muscle can develop ...

Hereditary non-polyposis colorectal cancer was diagnosed based on previously reported criteria and national ethics guidelines were followed (Johnson et al, 2005a, 2005b). A total of 77 HNPCC ...

Muscles contract thanks to the work of a protein called myosin. Using energy from adenosine triphosphate, this molecular motor works with fibrils of the protein actin to drive muscle contraction.

Does protein build muscle? The answer to this question is a resounding, ‘yes’. Muscle tissue is composed of a repeating structure of two protein filaments: myosin and actin. Myosin and actin filaments ...

Edgewise Therapeutics’ lead candidate has been shown to reduce levels of a biomarker related to skeletal muscle damage in a phase 2 trial. The biotech had been testing sevasemten, an orally ...

Cytokinetics Inc. has disclosed fast skeletal muscle myosin inhibitors reported to be useful for the treatment of Becker muscular dystrophy, Duchenne muscular dystrophy, facioscapulohumeral muscular ...