We next examined whether a 5′-dRP/AP lyase was also important in NHEJ of such substrates in cells. We used mouse dermal fibroblasts 13 deficient in Ku70 and p53, either complemented by expression of a ...
Phase I study of trametinib and neoadjuvant chemoradiation (CRT) in patients with locally advanced rectal cancers (LARC) that harbor KRAS, BRAF, or NRAS mutations. This is an ASCO Meeting Abstract ...
Une lyase est une enzyme capable de casser des liaisons covalentes, créant souvent de nouvelles doubles liaisons. Les lyases catalysent la cassure de liaisons covalentes, grâce à d'autres moyens que l ...
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