Researchers developed a way to directly reprogram human glial cells into PV interneurons without passing through a stem‑cell stage.

The brain's hippocampal region contains many classes of interneurons, which, it transpires, show different patterns of activity. They might contribute to memory by shaping the dynamics of neuronal ...

Researchers at the University of Virginia School of Medicine have uncovered how problems in cortical microcircuits in the brain can trigger epileptic seizures. The researchers say that targeting the ...

An LSU Health New Orleans research study led by Siqiong June Liu, PhD, Professor of Cell Biology and Anatomy, has found that cerebellar inhibitory interneurons are essential for fear memory, a type of ...

One hypothesis for the death of motor neurons in amyotrophic lateral sclerosis (ALS) is that the neurons become hyperexcited, firing overtime and ultimately being poisoned by their own activity (Rao ...

Researchers have successfully demonstrated how astroglia – cells that support the functioning of the brain – can be reprogrammed into cells resembling interneurons. The research, published in Science ...

A new study reveals how interneurons, dubbed 'the butterflies of the soul,' emerge and diversify in the brain. The findings may help inform the development of new classes of drugs for diseases such as ...

Labeling of intraregional synapses using LCD-eGRASP in the basolateral amygdala (BLA). Engram cells (Red), Non-engram cells (White), synapses from activated inhibitory interneurons (yellow), and ...

A molecular mechanism has been discovered that enables neuronal connections to change through experience, thus fueling learning and memory formation. The findings have the potential to reveal new ...

Striatal cholinergic interneurons (IMAGE) University of California - Irvine Caption The picture shows striatal cholinergic interneurons (cell body in yellow) whose neurites (in red) make multiple ...