Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes ...

Understanding human gene function in living organisms has long been hampered by fundamental differences between species.

A new research paper featured as the cover of Volume 17, Issue 12 of Aging-US was published on December 22, 2025, titled “A combination of differential expression and network connectivity analyses ...

A surprising amount of the DNA sequence in the genes of humans and other higher organisms ends up on the cutting-room floor, so to speak, spliced out by the cellular machinery that turns genetic code ...

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...

Findings on Fugu gene splicing could help scientists develop pufferfish transgenes for mammalian cells, say researchers at Massachusetts Institute of Technology. The Fugu genome contains all the ...

Discover the innovative TECHNO platform for full-length gene humanisation, enhancing models for human gene function.

In an important new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of ...

A new research paper featured as the cover of Volume 17, Issue 12 of Aging-US was published on December 22, 2025, titled "A combination of differential expression and network connectivity analyses ...

On some level, biology is all about regulation, regulation, regulation. One way that our cells regulate their genes is through a process called alternative splicing, which entails the selective ...