Narcolepsy is a disorder caused by losing orexin neurons, marked by excessive daytime sleepiness and cataplexy, sudden weakening of muscle tone. Previously, we found two kinds of neurons preventing ...

If you or someone in your household has narcolepsy, you know how much this condition can affect daily life. People with narcolepsy have fragmented nighttime sleep and extreme sleepiness during the day ...

Cataplexy is a sudden, brief loss of voluntary muscle tone triggered by strong emotions such as laughter, excitement, anger or fear. There is a strong association between cataplexy and narcolepsy, a ...

Cataplexy is a sudden episode of muscle weakness that occurs while fully aware and conscious. It can be triggered by emotional events, such as laughing, crying or fear, and is usually transient in ...

SAN DIEGO -- AXS-12 (reboxetine), an investigational treatment for narcolepsy, reduced weekly cataplexy attacks and in some cases provided complete remission, the phase III SYMPHONY study showed. From ...

SAN DIEGO — The investigational drug AXS-12 (reboxetine, Axsome Therapeutics) is safe and effective for the treatment of cataplexy (emotionally induced muscle weakness) and excessive daytime ...

And not figuratively, either. Sometimes people have found that certain emotions literally cause their muscles to unhook from their brains. They collapse entirely. This is not some strange disease, or ...

Sleep is of absolute necessity for us humans, although if one falls asleep all of a sudden while being awoken, it would cause a big trouble. The brain is equipped with sleep mechanism and wakefulness ...