Intervertebral disc degeneration is part of the natural ageing process and affects the structural and biomechanical properties of the spine 1,2. Previous research on the effects of degenerative disc ...

Karin Wuertz-Kozak described her lab test equipment as a gym for cells. Stretching and compressions tests using bioreactors—her lab equipment—can make a difference in understanding how cells respond ...

Usually the first step is conservative treatment. Patients who have radicular symptoms but who do not have weakness or myelopathy can be treated conservatively. Conservative treatment can include ...

Did you know that chronic lower back pain is the single greatest cause of years lived with disability worldwide? One of the main causes of lower back pain is lumbar degenerative disc disease. This is ...

Cleared on the basis of data from an IRB-approved study, SurGenTec’s ION-L facet is designed to provide a less invasive ...

Did you know that chronic lower back pain is the single greatest cause of years lived with disability worldwide? One of the main causes of lower back pain is lumbar degenerative disc disease. This is ...

To test the hypothesis that physical disruption of an intervertebral disc disturbs cell-matrix binding, leading to cell clustering and increased expression of matrix degrading enzymes that contribute ...

Low back pain resulting from degenerative disc disease is one of the most prevalent pathologies in the developed world. In the US, low back pain is the most common health problem for those younger ...

A recent study has unveiled the pivotal role of Ferroptosis Suppressor Protein 1 (FSP1) in intervertebral disc degeneration (IDD), a primary cause of chronic lower back pain. Researchers discovered ...

Phase I/II data of IDCT (rebonuputemcel), a cell therapy in development for chronic and progressive lumbar degenerative disc disease and one that has both regenerative medicine advanced therapy and ...

A new research paper was published in Volume 17, Issue 9 of Aging-US on September 8, 2025, titled, "Runx1 overexpression induces early onset of intervertebral disc degeneration." In this study, led by ...

Therapies that target aging cells early pave the way to easing back pain. "Once intervertebral discs start to degenerate, there is very little regeneration that happens," says Dr. Risbud. "But our ...