Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic tangles overwhelm normal repair pathways, cells flip on a fast but error-prone ...
Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...
New research led by researchers at the University of California, San Diego (UCSD), School of Medicine, reveals a novel map that depicts the human body’s system for addressing and repairing DNA ...
DNA repair is essential for the maintenance of genomic stability and its failure can lead to human disease. Various DNA repair systems exist, such as base excision repair, nucleotide excision repair, ...
Scientists have discovered a protein that can directly halt DNA damage. Better yet, a new study shows it appears to be 'plug and play', theoretically able to slot into any organism, making it a ...
Proteins PIF1 and PCNA gather at sites of DNA damage in SETX-deficient cells, indicating activation of the BIR repair system. LA JOLLA, CA—The DNA inside our cells is constantly being damaged, and one ...
New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human ...
“Our lab is generally interested in discovering and characterizing previously unknown or poorly understood factors that are essential for genome maintenance. This is particularly important in the ...
The tiny little powerhouses of our cells, the mitochondria, are unique among organelles because they carry their own tiny ...
DNA can be damaged by normal cellular processes as well as external factors such as UV radiation and chemicals. Such damage can lead to breaks in the DNA strand. If DNA damage is not properly repaired ...
Morning Overview on MSN
Aging immune cells may edit their own DNA to stay inflamed
As people grow older, their immune systems do not simply slow down, they often become locked into a simmering, ...
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