Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell's nucleus. The ...

Innovations in imaging and genetic engineering are coming together to probe the biophysics of cytoplasm inside living animals.

An international team of researchers has created the most detailed model yet of how cells regulate traffic through the nuclear pore complex—the gateway between a cell’s nucleus and its cytoplasm. The ...

UC Davis researchers tracked the movement of fluorescent particles inside the cells of microscopic worms, providing novel insights into cellular crowding in a multicellular animal. They found that the ...

In living cells, regulation of the electrochemical environment is supposed to be managed by ion channels—protein complexes that reside in cell membranes and assume definite shapes. So, it’s surprising ...