Sequencing circulating tumor cell-free DNA (cfDNA) in cerebrospinal fluid (CSF) improved diagnosis, decision-making, and clinical care in pediatric and adolescent and young adult (AYA) patients with ...
CSF-ctDNA was detected in 59% of cases and showed high concordance (84%) with tumor mutations. Lower variant allelic frequency in CSF-ctDNA was associated with significantly worse survival outcomes.
More than 20 y ago, we developed an animal model for chronic and continuous collection of cerebrospinal fluid (CSF) from conscious rhesus macaques. Since our previous publication in 2003, we have ...
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Dried blood samples match CSF accuracy in Alzheimer's detection
A technology that diagnoses various diseases, including Alzheimer’s and Parkinson’s, using just a few drops of blood from a finger prick is called “blood biomarker measurement.” In recent years, ...
The Association of Primate Veterinarians (APV) recognizes that CSF collection may be required for both clinical and research purposes in nonhuman primates (NHP). Because there are inherent risks ...
Cerebrospinal fluid (CSF) is a type of clear liquid that surrounds, protects, and cushions your brain and spinal cord from possible injuries. The fluid is held in place by the dura mater, a dense ...
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