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Ageing slows brain protein clearance and shifts synaptic waste to microglia
By Vijay Kumar Malesu New mouse data reveal that ageing neurons struggle to clear synaptic proteins, shifting the burden to ...
Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when the cellular ...
F.-U. Hartl, W. Neupert, "Protein sorting to mitochondria: evolutionary conservations of folding and assembly," Science, 247:930-38, 1990. Franz-Ulrich Hartl (University of Munich, Germany): "In this ...
Northwestern Medicine scientists have zeroed in on a cellular gatekeeper that may hold promise for treating abnormal protein ...
Poly(N-isopropylacrylamide) (PNIPAM) hydrogel undergoes significant but precise changes in size between 20°C and 40°C, making it an excellent candidate for use in variable-size deterministic lateral ...
Attendees will see some common applications of cell sorting in a department of immunology. Beginning with an introduction of lymphoproliferative disorders in inborn errors of immunity. 1. How cell ...
Yet proteins play different roles in the different cellular and tissue contexts in which they find themselves and also depending on whether the same tissue or cell is healthy or diseased.
Cellular membrane proteins play many important roles throughout the body, including transporting substances in and out of the cell, transmitting signals, speeding up reactions and helping neighboring ...
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