Tumor cells use a variety of mechanisms to evade detection and destruction by the immune system. CD59—a complement regulatory protein that inhibits complement-mediated lysis of target cells—is ...

CD59 is a potent inhibitor of the complement membrane attack complex (MAC) action that acts by binding to the C8 and C9 complements of the assembling MAC, thereby preventing incorporation of the ...

A study shows promise in slowing age-related macular degeneration (AMD). Researchers demonstrate for the first time that a gene therapy approach to deliver CD59, an inhibitor of complement, can ...

One of the frustrations for scientists working on HIV/AIDS treatments has been the human immunodeficiency virus' ability to evade the body's immune system. Now a researcher has discovered a compound ...

Protection of self cells is conferred principally by intrinsic cell surface regulators. These molecules are the decay-accelerating factor (DAF or CD55), membrane cofactor protein (MCP or CD46), and ...

BOSTON (April 29, 2011) — A gene therapy approach using a protein called CD59, or protectin, shows promise in slowing the signs of age-related macular degeneration (AMD), according to a new in vivo ...