The Trump administration is warning Harvard University that it could take over its patents, worth hundreds of millions of dollars, if a review finds the university hasn’t complied with federal law, an escalation of the continuing negotiations between the White House and America’s oldest university.

After losing nearly $3 billion in research funding, Harvard University now risks losing control of its intellectual property in a latest Trump administration action.

The Commerce Department is launching an immediate review of the intellectual property Harvard has derived from federally funded research grants.